Dr. Ryan Trowbridge, board-certified dermatologist, says that Accutane (isotretinoin) is the most-effective FDA-approved treatment to treat severe acne, particularly nodular or cystic acne that hasn’t responded to other treatments. What is Accutane? Accutane is a form of vitamin A. It reduces the amount of oil released by oil glands in your skin, and helps your skin renew itself more quickly. Accutane is used to treat severe nodular acne that has not responded to other treatments, including antibiotics. Accutane generic (Isotretinoin) is an oral retinoid used for severe nodular or cystic acne that has not responded to standard topical or oral treatments. It works by reducing sebaceous gland size and oil production, preventing clogged pores, and lowering inflammation. What is Accutane? Isotretinoin is a potent derivative of vitamin A that shrinks oil glands in the face, chest, back, shoulders and upper arms, says Dr. Richard Antaya, director of pediatric. Some people refer to this medication as Accutane ®. This is a brand of isotretinoin that is no longer available. Warning: When you buy this medication from an online site that does not require a prescription, you put your health at serious risk. One course of treatment takes about four to five months. Accutane® (Isotretinoin) is a type of retinoid medication that treats severe acne. A healthcare provider may prescribe this medication if other acne medications don’t work. Isotretinoin is a prescription medication used to treat severe recalcitrant nodular acne. While isotretinoin is beneficial for some patients, there are risks associated with this drug. Overview: Isotretinoin is used to treat acne. It reduces oil on your skin and changes how your skin cells grow and shed so they do not clog pores or form acne. Common side effects may include. Isotretinoin is used to treat severe, disfiguring nodular acne. It should be used only after other acne medicines or antibiotics have been tried and have failed to help the acne. Isotretinoin may also be used to treat other skin diseases as determined by your doctor. What It Is: Isotretinoin, often known by its brand name Accutane ®, is an oral medication approved for severe, scarring acne that is normally prescribed for 15-20 weeks.